Backing the next generation of industry defining companies.

We partner with founders building companies across AI-enabled software, applied technologies, and life sciences focused on solving complex, real world problems in undercapitalized markets.

R1 Capital is led by a team that has invested together for over a decade across multiple fund cycles, through a consistent and disciplined approach to early-stage investing. R1 invests across stages, partnering with founders to support creation, validation, and growth with the network and resources needed to build enduring businesses. With Midwest roots and national reach, R1 works alongside Rev1 Ventures' studio and a deep venture partner network to deliver hands-on support and a platform that extends well beyond capital. R1 backs founders at defining moments - where potential becomes motion and momentum becomes measurable.
Over the past decade, the R1 Capital team has supported more than 150 startups, helping founders build, validate, and scale companies across multiple technology cycles.

“R1 Capital encouraged open dialogue around critical topics early and often. That kind of communication has been important to me as we have advanced the company and continued making decisions about the path ahead.”

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Dave Richards, CEO | Clarametyx

“R1 Capital added value beyond capital. They made introductions, shared their network, and took the time to understand what we were after as Ohio founders building a company for the long term.”

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Jason Berwanger, Co-Founder & CEO | HubiFi

“R1 Capital introduced us to other investors, helped us prepare for those conversations, and ultimately helped us find the lead investor for our seed round. I don’t know if we would have found that relationship without them.”

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Luke Buchanan, Co-Founder & CEO | Redi Health

“In life sciences, not everything goes perfectly. You need resilient teams and experienced people around the table who can help you think through difficult decisions. That’s one of the things we value most about working with R1.”

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Joe Bagan, Co-founder & Chief Executive Officer | STAQ Pharma

“There has never been a better opportunity to build a truly world-impacting company from anywhere. But building often requires capital, and having local investors like R1 Capital who support talented builders in this region can help produce some really impactful companies.”

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Dan Manges, Co-Founder | RWX

“What stood out about R1 was the quality of the people leading the work. These were credible advisors, former and current entrepreneurs who had been around the block and could speak from real operating experience.”

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Paul Grimm, CEO | Myoptechs

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